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I am 56 and I was diagnosed with breast cancer about three years ago. And it was definitely a shock for me. I used to live calm and happy life, wonderful husband, healthy kids, nice job. And suddenly - cancer? It was a blast. First period I was extremely depressed. I had no power to start thinking about any treatment or medications. I couldn't imagine my future. I couldn't understand why. Now I understand that this period was just as hard for my family members as for me. However both they and my doctors were extremely gentle and patient to me. They gently talked me into tests, check-ups, therapy and medicamental treatment. Now the most horrible period is over. I learnt to live with cancer diagnosis and I even got hope to conquer it. I had undergone a therapy course in Germany, that was highly effective - cancer cells stopped to grow and multiply. I started feeling myself much better. After I was back from Germany my doctor prescribed me with Xtane and the drug performs really good at keeping cancer from further growth. The lucky moment was that my cancer was diagnosed at an early stage when the risk was not extremely high and I still hope I won't need mastectomy... I really believe that with Xtane I'll cope with my disease. And I want all women with breast cancer never to lose hope and to continue struggling.

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There was no interaction between density and sequence.

Between Nov 7, 2003, and April 7, 2011, 4717 premenopausal women with hormone-receptor positive breast cancer were enrolled in TEXT or SOFT to receive unmasked adjuvant treatment with 5 years of exemestane plus OFS or tamoxifen plus OFS.

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Do you recommend both IV and IP (intraperitoneal) chemotherapy for me?

Some women choose mastectomy over breast-conserving treatment even if the latter is appropriate because it gives them a greater sense of security and allows them to avoid radiation therapy.

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Generally, women with early breast cancer can take exemestane after two to three years of taking tamoxifen.

It should not be used for BC risk reduction in premenopausal women.

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Adjuvant Chemotherapy and Hormonal Therapy for Older Adults With Breast Cancer.

Perhaps the greatest benefit is the gradual reduction in stress experienced as a result of my on-going stabilised condition after a lumpectomy.

This is an uncomfortable and sometimes painful side effect of hormone treatment.

No limitations of procedure or protocol were observed during the conduct of this study.

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All three are very similar and while all three carry slight differences that make them unique many agree Arimidex may be the most valuable of all.

The median time from randomization to off-protocol treatment was 10.

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Arimidex is a newer drug and doctors wanted to see whether it could work better than tamoxifen.

Radiation therapy reduced the occurrence of invasive cancer from 16.

This recommendation applies to asymptomatic women aged 35 years or older without a prior diagnosis of breast cancer, DCIS, or LCIS.

The beneficial effect of tamoxifen on breast cancer persisted after active treatment, with a median posttherapy follow-up of 46 months; 27% fewer women in the tamoxifen arm developed breast cancer (142 vs.

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Table 4 shows the adverse reactions of all CTC grades, regardless of causality, reported in 5% or greater of patients in the study treated either with AROMASIN or megestrol acetate.

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The Southwest Oncology Group (SWOG) confirmed the results of several other neoadjuvant trials in that ER-negative tumors have a higher pCR compared with ER-positive tumors and that infiltrating ductal histologies have a higher pCR rate compared with infiltrating lobular histologies.

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Guidelines from the American Society for Reproductive Medicine (2013) state that in vitro maturation should only be performed as an experimental procedure in specialized centers for carefully selected patients evaluatinb both efficacy and safety.

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Age-related alterations in exemestane pharmacokinetics were not seen over this age range.

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Explanation for this discrepancy was recently provided by a retrospective review of several NSABP trials, which found that there was significant concordance between the ER-status of the primary breast cancer and that of contralateral breast cancer.

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In the BOLERO-3 trial, 569 patients with HER2-positive, trastuzumab-resistant breast cancer, who had received previous taxane therapy, were randomly assigned to receive either everolimus plus trastuzumab plus vinorelbine, or placebo plus trastuzumab plus vinorelbine.

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The rest of my body is slowly getting there, but some days I feel about 80, I get stiff a lot and achy sore muscles, I think I am just great fun to be alive that I can live with the other problems.

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All the patients in TEXT and the patients in SOFT who did not receive chemotherapy underwent randomization within 12 weeks after definitive surgery; patients in SOFT who received adjuvant or neoadjuvant chemotherapy underwent randomization within 8 months after completing chemotherapy, once a premenopausal level of estradiol was confirmed.

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ASCO guidelines agree with those and further suggest BMD screening for women with breast cancer who have high risk factors such as family history of fractures, body weight less than 70 kg, and prior non-traumatic fracture, for postmenopausal women of any age receiving aroma-tase inhibitor (AI) therapy, and for premenopausal women with therapy-induced ovarian failure.

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There have been studies done in mice showing tamoxifen mimic the effects of estrogen on bone metabolism and skeletal growth.

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